Guillain-Barré Syndrome-Related Campylobacter jejuni in Bangladesh: Ganglioside Mimicry and Cross-Reactive Antibodies
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منابع مشابه
Guillain-Barré Syndrome-Related Campylobacter jejuni in Bangladesh: Ganglioside Mimicry and Cross-Reactive Antibodies
BACKGROUND Campylobacter jejuni is the predominant antecedent infection in Guillain-Barré syndrome (GBS). Molecular mimicry and cross-reactive immune responses to C. jejuni lipo-oligosaccharides (LOS) precipitate the development of GBS, although this mechanism has not been established in patients from developing countries. We determined the carbohydrate mimicry between C. jejuni LOS and ganglio...
متن کاملCampylobacter jejuni HS:23 and Guillain-Barré Syndrome, Bangladesh
Regina Schuhegger, Christoph Schoerner, Julia Dlugaiczyk, Ina Lichtenfeld, Alexander Trouillier, Veronique Zeller-Peronnet, Ulrich Busch, Anja Berger, Rudolf Kugler, Stefan Hörmansdorfer, and Andreas Sing Author affiliations: National Consiliary Laboratory for Diphtheria, Oberschleißheim, Germany (R. Schuhegger, A. Berger, R. Kugler, A. Sing); Bavarian Health and Food Safety Authority, Oberschl...
متن کاملCampylobacter jejuni infection and Guillain-Barré syndrome.
BACKGROUND Although infection with Campylobacter jejuni is recognized as a common antecedent of the Guillain-Barré syndrome, the clinical and epidemiologic features of this association are not well understood. METHODS We performed a prospective case-control study in a cohort of patients with Guillain-Barré syndrome (96 patients) or Miller Fisher syndrome (7 patients) who were admitted to hosp...
متن کاملGuillain--Barré syndrome and Campylobacter jejuni infection.
1. SUMMARY Guillain±Barre  syndrome (GBS) is the most common cause of acute neuromuscular paralysis, usually due to acute in¯ammatory demyelinating polyradiculoneuropathy. The presence of activated T lymphocytes and antibodies against peripheral nerve myelin suggests an autoimmune patho-genesis, although there is wide heterogeneity. Gangliosides are sialylated glycolipids widely distributed in...
متن کاملLipopolysaccharides from Campylobacter jejuni O:41 strains associated with Guillain-Barré syndrome exhibit mimicry of GM1 ganglioside.
Three Campylobacter jejuni, biotype 2, serotype O:41 strains that were isolated from patients who developed Guillain-Barré syndrome (GBS) and one C. jejuni isolate from a patient who developed enteritis only were examined. The aim of the study was to determine the structure of the core oligosaccharide (OS) of the lipopolysaccharide (LPS) of C. jejuni serotype O:41, a serotype rarely associated ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0043976